What phenomenon is described by the body's increased sensitivity to alcohol after long-term use?

The phenomenon described by the body's increased sensitivity to alcohol after long-term use is known as reverse tolerance. This occurs when an individual who has consumed alcohol over a prolonged period begins to experience its effects more intensely even at lower doses. Reverse tolerance can develop due to various factors, including physiological changes in liver function, alterations in how the brain processes alcohol, or a potential reduction in body mass or hydration levels, making the substance affect the body more significantly.

Understanding reverse tolerance is important in the context of addiction treatment because it highlights that individuals might require less alcohol to achieve the same effects they once experienced with higher quantities, which can increase the risk of alcohol-related harms. This concept can play a significant role in assessing an individual's relationship with alcohol and guiding interventions to promote safer behaviors and recovery approaches.