What does the concept of tolerance imply about substance use?

The concept of tolerance in the context of substance use refers to a process where an individual requires increasing amounts of a substance to achieve the same effects that they initially experienced with lower doses. This phenomenon occurs because the body adapts to the presence of the substance, leading to diminished response over time.

As a person continues to use a substance, their nervous system and body may adjust in ways that lessen the drug's effects, prompting the individual to consume larger quantities to achieve the desired outcome. For instance, someone who regularly uses alcohol may find that over time, they need to drink more to feel intoxicated as their body becomes accustomed to its effects. This principle plays a significant role in addiction, as tolerance can lead to increased substance use and, potentially, dependence.

Other concepts, like maintaining the same dosage without effect, minimizing use without consequences, or tolerance eliminating withdrawal symptoms, do not accurately describe the nature of tolerance in addiction. In fact, tolerance is often accompanied by withdrawal symptoms when substance use is decreased or ceased, illustrating the complexity of the relationship between use, tolerance, and dependence.